CAFFEINE AS A TOOL FOR INVESTIGATING THE INTEGRATION OF CDC25 PHOSPHORYLATION, ACTIVITY AND UBIQUITIN-DEPENDENT DEGRADATION IN SCHIZOSACCHAROMYCES POMBE

Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe

Abstract The evolutionarily conserved Cdc25 phosphatase is an essential protein that removes inhibitory phosphorylation moieties on the mitotic regulator Cdc2.Together with the Wee1 kinase, a negative regulator of Cdc2 activity, Cdc25 is thus a central regulator of cell cycle progression in Schizosaccharomyces pombe.The expression and activity of C

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Social network-based group intervention to promote uptake of cervical cancer screening in Uganda: study protocol for a pilot randomized controlled trial

Abstract Introduction Cervical cancer (CC) is the most common cancer and accounts for one quarter of all cancer-related deaths among women in Uganda, where lifetime CC screening is estimated to be as low as 5%.This study will evaluate the feasibility, acceptability, and preliminary efficacy of a social network-based group intervention designed to e

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